MateriAlZ Seminar: Sudipta Seal
Friday, April 7, 2023 - 10:45 a.m. MST
Sudipta Seal
Professor and Chair
Materials Science and Engineering
University of Central Florida
"Vacancy Engineered Nano-Rare Earth Oxides: Implications in Bio-Catalysis"
Zoom link; Passcode: 22685
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Abstract
Engineered rare earth oxide nanoparticles (e.g., ceria) having mixed valences on their surface are found to be redox active. In case of nanoceria, such vacancies can scavenge excess reactive oxygen species (ROS), due to their redox active nature. However, it is very important how to synthesize such vacancy rich nanostructures. Specially designed nanoceria mimics the catalytic properties of antioxidative enzymes and induces protective effect through regenerative scavenging potential and ameliorates the disease states further. Based on its design methodology, nanoceria has been developed for scavenging of different reactive oxygen species (ROS) and reactive nitrogen species (RNS) molecules including superoxide anions, hydrogen peroxide. Both ab initio and classical computer modeling, together with the experiment, is used to design structures for nanoceria that maximize its nanozymetic activity. Various examples on the use of nanoceria in wound healing, radioprotection is presented.
Bio
Dr. Seal, FASM, University Distinguished Professor, Trustee Chair and UCF Pegasus Professor, joined University of Central Florida (UCF) in the fall of 1997 after postdoctoral work at Lawrence Berkeley National Laboratory. He served as a Director of Advanced Materials Processing Analysis Center, and Nanotechnology Center, currently chair of the newly created materials science and engineering and holds an appointment with College of Medicine. He is the recipient of the 2002: Office of Naval Research Young Investigator Award (ONR-YIP), JSPS fellowship, Alexander Von Humboldt Fellow, ASM IIM Lecturer award, Royal Soc of Eng - Visiting Professor Distinguished Fellowship at Imperial College, UK, etc. He was elected to attend the Frontiers of Eng Symposium by National Academy of Engineering. He is the recipient of Fellow of FASM, FAAAS, FAVS, FIoN, FAIMBE, FNAI, FECS, FMRS, FRSC, FACERS. He is inducted to the Florida Hall of Fame of Inventors, elected World Academy Ceramics Academician and a recent recipient of ASM International Albert Sauveur Materials Achievement Award. He has more than 400 journal papers, books and h index> 104. He has more than 84 issued patents and his technology is responsible for various startups.